Downsizing the Paramecium genome
نویسندگان
چکیده
منابع مشابه
Genome Evolution: A Double Take for Paramecium
The surprising discovery of a whole-genome duplication in the otherwise compact genome of Paramecium tetraurelia displays the early forces driving gene retention and loss.
متن کاملParamecium genome survey: a pilot project.
A consortium of laboratories undertook a pilot sequencing project to gain insight into the genome of Paramecium. Plasmid-end sequencing of DNA fragments from the somatic nucleus together with similarity searches identified 722 potential protein-coding genes. High gene density and uniform small intron size make random sequencing of somatic chromosomes a cost-effective strategy for gene discovery...
متن کاملEvaluating the role of genome downsizing and size thresholds from genome size distributions in angiosperms.
PREMISE OF THE STUDY Whole-genome duplications (WGDs) can rapidly increase genome size in angiosperms. Yet their mean genome size is not correlated with ploidy. We compared three hypotheses to explain the constancy of genome size means across ploidies. The genome downsizing hypothesis suggests that genome size will decrease by a given percentage after a WGD. The genome size threshold hypothesis...
متن کاملNucleotide sequence of the mitochondrial genome of Paramecium
The nucleotide sequence for 40,469 bp of the linear Paramecium aurelia mitochondrial (mt) genome is presented with the locations of the known genes, presumed ORFs, and their transcripts. Many of the genes commonly encoded in mt DNA of other organisms have been identified in the Paramecium mt genome but several unusual genes have been found. Ribosomal protein genes rps14, rps12, and rpl2 are clu...
متن کاملExtraordinary genome stability in the ciliate Paramecium tetraurelia.
Mutation plays a central role in all evolutionary processes and is also the basis of genetic disorders. Established base-substitution mutation rates in eukaryotes range between ∼5 × 10(-10) and 5 × 10(-8) per site per generation, but here we report a genome-wide estimate for Paramecium tetraurelia that is more than an order of magnitude lower than any previous eukaryotic estimate. Nevertheless,...
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ژورنال
عنوان ژورنال: Genome Biology
سال: 2000
ISSN: 1465-6906
DOI: 10.1186/gb-spotlight-20001109-02